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HERE FOR YOU Age-related fertility decline can be hard to face, but at London Women’s Clinic great care is taken to give women the best possible chance of success
For patients who have been through multiple failed IVF cycles, the answer is rarely just more hope. London Women’s Clinic explains how genetic embryo testing is changing what’s possible WHEN SCIENCE STEPS IN
S arah had done everything right: the fertility appointments, lifestyle changes, multiple tests and all the research. She had lost twin boys at 22 weeks, suffered a miscarriage and had two failed embryo transfers. When she and her husband approached their third IVF cycle at London Women’s Clinic, their consultant recommended pre-implantation genetic testing for aneuploidy, which is also known as PGT-A. An American research study estimates that PGT-A in the US avoided nearly 15,000 miscarriages and more than 6,500 preterm births in 2023. 1 At London Women’s Clinic, for women over 37 the chances of having a live birth when transferring a euploid (chromosomally normal) embryo following PGT-A have equal chances to
PGT-A is not the answer for everyone, and at London Women’s Clinic it’s never a default. But for those over 37, those who have had recurrent miscarriage or those facing repeated failed embryo transfers, it can offer valuable information.
those for women under 37, 2 a statistic that demonstrates how this test can reverse the impact of age-related fertility decline. PGT-A analyses embryos at the blastocyst stage (five to six days after fertilisation), identifying which have the correct number of chromosomes. This factor is invisible to the naked eye, and it’s a common reason that an IVF cycle may result in a miscarriage. Of four of Sarah’s embryos that were tested, two were found to be chromosomally normal, and after a final IVF cycle a further three were. In January 2024, the highest quality of those embryos was transferred. That embryo became Sarah’s son, now 15 months old. “I always held on to the hope that it would happen. I kept focusing on the end goal,” says Sarah, LWC patient.
To find out more about PGT-A or to book a consultation at London Women’s Clinic Cambridge, based at 52 Mawson Road CB1 2HY , visit londonwomensclinic.com
1 Griffin, D., Mcwilliams, K., Munné, S., & Gordon, A. (2025). Preimplantation genetic testing for aneuploidy (PGT-A) in the USA avoided nearly 15 000 miscarriages and over 6500 preterm births in 2023: an opinion. BMJ Connections Clinical Genetics and Genomics, 2(1), e000053 2 Data from Kind IVF patients 2022-2024 and LWC patients with PGT 2019-2024
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