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New technologies for the genomics toolbox of the future
or almost a decade, CRISPR has dominated discussion within scientific communities.
MULTIDISCIPLINARY The Advanced Courses and Scientific Conferences programme brings together scientific communities from a variety of research and clinical backgrounds, including healthcare professionals working in genomics. data visualisation and analysis that sets a new precedent for studying and interpreting thousands of cells at once to draw detailed conclusions. Thanks to this, we are now closer than ever to laying the foundations for precision medicine, with many opportunities for organisations working in genome targeting and novel drug development. “It is an incredibly exciting time to work in biomedical science. We can now systematically knock out every gene in the genome or mutate every DNA base in disease-causing genes, and couple this with novel rich readouts from cells and organisms to understand how changes in DNA lead to disease,” explains Dr Leopold Parts, group leader, Wellcome Sanger Institute. “Our conference will cover the technologies that enable these approaches, and showcase their applications in basic research, medicine and drug development.” These pioneering technologies are a core topic for the forthcoming CRISPR and Beyond: Perturbations
Once a theme reserved for science fiction, it’s becoming a reality as a viable biotech solution to many genetic challenges facing the future of healthcare. Black holes and revelations Thanks to large-scale genome sequencing, we now have deep catalogues of natural and disease- related human genetic variation. However, a lack of understanding around the function of a vast majority of the detected variants is delaying the progress to enable us to answer long- standing (sometimes urgent) important questions about human health. CRISPR opportunities: the key to unlocking greater understanding Significant advances in CRISPR technologies now make it possible to integrate such gene editing power with single-cell sequencing methods. A formidable combination between
HIGHLIGHT SPEAKERS Britt Adamson
University of Princeton, US Interrogating gene function with high-resolution functional genomics. Fritz Roth University of Toronto, Canada Prospects for testing all possible human missense variants in every disease gene. Maya Ghoussaini OpenTargets, UK Using genetics and genomics to prioritise drug targets. professional colleagues, decision makers, and high-profile speakers and thought leaders. ACCESS To target rich environments containing established researchers and clinicians, as well as rising members of diverse genomics and biomedical communities. Interact in the comfort zone of many
IMAGES The CRISPR conference is a
chance to network with top scientists and health professionals
NETWORKING Meet and mingle with field experts,
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